These are manually curated databases that scan the published references for experimental evidences related with the regulatory effect of a particular miRNA over its cognate targets. Some of them allow to search for several criteria, including the experimental methods used for target validation.
App/WEB |
Comments |
Species covered | Reference |
---|---|---|---|
miRTarbase |
contains more than 3000 miRNA-target interactions (MTIs), which are collected by manually surveying pertinent literature after data mining of the text systematically to filter research articles related to functional studies of miRNAs. Contains a customizable search engine that allows personalized data mining using several parameters including the experimental technique used to validate miRNA targets. | 18 species including Human, mouse, rat, fly, viruses and plant models |
PMID: 26590260 |
miRWalk2 |
A comprehensive database that provides information on miRNA from Human, Mouse and Rat on their predicted as well as validated binding sites on their target genes combining eight different applications for target prediction. | Human, mouse and rat | PMID: 26226356 |
Tarbase |
This database hosts detailed information for each miRNA–gene interaction, ranging from miRNA- and gene-related facts to information specific to their interaction, the experimental validation methodologies and their outcomes. | 28 species including Human, mouse, rat, fly, viruses and plant models | PMID: 27603020 |
Starbase2 |
StarBase is designed for decoding Pan-Cancer and Interaction Networks of lncRNAs, miRNAs, competing endogenous RNAs(ceRNAs), RNA-binding proteins (RBPs) and mRNAs from large-scale CLIP-Seq (HITS-CLIP, PAR-CLIP, iCLIP, CLASH) data and tumor samples (14 cancer types, >6000 samples). | Human | PMID: 24297251 |
miRecords |
Resource for animal miRNA-target interactions. miRecords consists of two components: a database of validated targets and a combined resource which simultaneously uses eleven applications for miRNA target prediction, and multiple species. | Human, mouse and rat | PMID: 18996891 |